Trop BRC IPB University: There are 125 Prospective Herbal Compounds to Prevent COVID-19

Jamu as our national heritage needs a special attention from its upstream and downstream sector, especially at the pandemic period. That matter encouraged The Tropical Biopharmaca Research Center (TROP BRC) Institute of Research and Community Service (LPPM), IPB University to hold a discussion themed “Strategy of Jamu Modernization to Face New Normal”, (9/6) via Zoom and youtube streaming. The strategic roles of traditional medicine include in health, technology, economy, and socio-cultural aspect. In developing modernization of Jamu, jamu café could also become an alternative to make it attractive for millennial generation. Nowdays, jamu is not only being sold conventionally, but also being sold via online.

That matter was explained by Dra Rr Maya Gustina Andarini MSc, The Deputy of Supervision of Traditional Medicine, Health Supplements, and Cosmetics from BPOM RI while she was explaining about “The role of BPOM Traditional Medicine Modernization to Face New Normal”.

According to her, The BPOM support is to assist researchers. BPOM will assist them from the protocol making step by providing expert team. “We will strive together to make traditional jamu be included in KORNAS. If it can be covered by BPJS, the price will decrease and the demand will increase. If the raw material could be fulfilled, the excess can be exported to introduce traditional jamu in many countries. We need to strive together to optimize the role of traditional jamu,” she explained.

Meanwhile, Dr Siti Sa’diah, Apt.m Msi, lecturer of IPB University from Departement of Anatomy, Physiology and Pharmacology, Faculty of Veterinary Medicine, explained that through the vision of jamu development, they hope that the quality of jamu will be better.

“If we still depend on the foreign countries, we will not have security in medicine,” she expalined while doing a review about “Globalization of Jamu in Pandemic Period: The Opportunities and  Threats”.

COVID-19 pandemic has encouraged many researchers to study natural commodities in order to search for new prospective medicines through big data analysis approaches using machine learning and pharmacophore modelling to obtain potential materials.

“Through this technical approach, it is possible to quickly obtain potential plant based on its active compounds, which potentially effective against targeted proteins of COVID-19 virus, computationally. The result from machine learning process showed that there are 125 prospective herbal compounds which have potential to prevent COVID-19,” said Dr Siti Sa’diah.

Through screening by machine learning, pharmacophore modelling, and main protease docking, it showed that some of the prospective compounds are: Hesperidine, Myricetin-3, Peonidine, Quercertin 3, Rhamnetin3 and Kaemferol 3. Those compounds could be found in red guava, orange peel, and moringa leaf.

In her presentation, Dr Siti Sa’diah also explained about opportunities and threats of traditional jamu. The opportunities are, high interest from the society to consume jamu, already being accepted by millennial generation, potential market (local and global), and also the potential of raw material. Whereas, the threats are, illegal jamu circulation in the market, and innovation of the packaging to make the product attractive. (IAAS/ISL)

Published Date : 10-Jun-2020

Resource Person : Dr Siti Sa’adah

Keyword : Biopharmaca Research Center, LPPM, IPB University, herbal medicine, herbal potential to prevent COVID, lecturer of IPB